ETS2 Antibody
| Code | Size | Price |
|---|
| PSI-64-143-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Protein C-ets-2, ETS2
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Background:
ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes.
Background References:
- Zabuawala, T., et al. Cancer Res. 70(4):1323-1333(2010)
- Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
- Shalaby, A.A., et al. Mod. Pathol. 22(8):996-1005(2009)
- Sutter, W., et al.Craniomaxillofac Surg 37(5):263-271(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This ETS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-173 amino acids from the Central region of human ETS2.
NCBI Gene ID #:
2114
NCBI Official Name:
Protein C-ets-2
NCBI Official Symbol:
ETS2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
P15036
Protein GI Number:
119645
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,
Swissprot #:
P15036
User NOte:
Optimal dilutions for each application to be determined by the researcher.