PLG Antibody

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ProSci
Product Code: PSI-62-814
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-62-814-400ul400ul£626.00
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

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Western blot analysis of lysate from human blood plasma tissue lysate, using PLG Antibody at 1:1000 at each lane.
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Western blot analysis of lysate from human blood plasma tissue lysate, using PLG Antibody at 1:1000 at each lane.

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Further Information

Additional Names:
Plasminogen, Plasmin heavy chain A, Activation peptide, Angiostatin, Plasmin heavy chain A, short form, Plasmin light chain B, PLG
Application Note:
For WB starting dilution is: 1:1000
Background:
PLG is a circulating zymogen that is converted to the active enzyme plasmin by cleavage of the peptide bond between arg560 and val561, which is mediated by urokinase and tissue plasminogen activator. The main function of this protein is to dissolve fibrin clots. The protein, like trypsin, belongs to the family of serine proteinases.
Background References:
  • Hofmann,S.C., Voith,U. J. Invest. Dermatol. 129 (7), 1730-1739 (2009)
  • Passero,C.J., Mueller,G.M. J. Biol. Chem. 283 (52), 36586-36591 (2008)
  • Ohyama,S., Harada,T. Eur. J. Biochem. 271 (4), 809-820 (2004)
  • Lee,H., Kim,H.K. Arch. Biochem. Biophys. 375 (2), 359-363 (2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PLG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-175 amino acids from the N-terminal region of human PLG.
NCBI Gene ID #:
5340
NCBI Official Name:
Plasminogen
NCBI Official Symbol:
PLG
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
91 kDa
Protein Accession #:
P00747
Protein GI Number:
130316
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Cell Cycle
Swissprot #:
P00747
User NOte:
Optimal dilutions for each application to be determined by the researcher.