PRPS2 Antibody

ProSci
Product Code: PSI-58-473
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-473-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in K562 cell line lysates (35ug/lane).
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Western blot analysis of PRPS2 using rabbit polyclonal PRPS2 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PRPS2 gene.

Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis of PRPS2 using rabbit polyclonal PRPS2 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PRPS2 gene.

Further Information

Additional Names:
Ribose-phosphate pyrophosphokinase 2, PPRibP, Phosphoribosyl pyrophosphate synthase II, PRS-II, PRPS2
Application Note:
For WB starting dilution is: 1:1000
Background:
PRPS2 is a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants.
Background References:
  • Mannava, S., et al. Cell Cycle 7(15):2392-2400(2008)
  • Tatibana, M., et al. Adv. Enzyme Regul. 35, 229-249 (1995) :
  • Dawson, S.J., et al. J. Infect. 24(3):317-320(1992)
  • Ishizuka, T., et al. Biochim. Biophys. Acta 1130(2):139-148(1992)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Y, Bovine, Monkey, Mouse, Rat, Xenopus
Immunogen:
This PRPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the Central region of human PRPS2.
NCBI Gene ID #:
5634
NCBI Official Name:
Ribose-phosphate pyrophosphokinase 2
NCBI Official Symbol:
PRPS2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
35 kDa
Protein Accession #:
P11908
Protein GI Number:
125583
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle
Swissprot #:
P11908
User NOte:
Optimal dilutions for each application to be determined by the researcher.