SMC3 Antibody
| Code | Size | Price |
|---|
| PSI-58-027-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Structural maintenance of chromosomes protein 3, SMC protein 3, SMC-3, Basement membrane-associated chondroitin proteoglycan, Bamacan, Chondroitin sulfate proteoglycan 6, Chromosome-associated polypeptide, hCAP, SMC3, BAM, BMH, CSPG6, SMC3L1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene belongs to the SMC3 subfamily of SMC proteins.
The encoded protein occurs in certain cell types as either an
intracellular, nuclear protein or a secreted protein. The nuclear
form, known as structural maintenance of chromosomes 3, is a
component of the multimeric cohesin complex that holds together
sister chromatids during mitosis, enabling proper chromosome
segregation. Post-translational modification of the encoded protein
by the addition of chondroitin sulfate chains gives rise to the
secreted proteoglycan bamacan, an abundant basement membrane
protein.
Background References:
- Pie, J., et al. Am. J. Med. Genet.152A (4), 924-929 (2010) :
- Terret, M.E., et al. Nature 462(7270):231-234(2009)
- Revenkova, E., et al. Hum. Mol. Genet. 18(3):418-427(2009)
- Ridinger, H., et al. Exp. Mol. Pathol. 86(1):23-31(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This SMC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-430 amino acids from the Central region of human SMC3.
NCBI Gene ID #:
9126
NCBI Official Name:
Structural maintenance of chromosomes protein 3
NCBI Official Symbol:
SMC3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
142 kDa
Protein Accession #:
Q9UQE7
Protein GI Number:
29337005
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle
Swissprot #:
Q9UQE7
User NOte:
Optimal dilutions for each application to be determined by the researcher.