FBXO31 Antibody

ProSci
Product Code: PSI-58-919
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-919-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).

Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).

Further Information

Additional Names:
F-box only protein 31, FBXO31, FBX14, FBX31
Application Note:
For WB starting dilution is: 1:1000
Background:
Members of the F-box protein family, such as FBXO31, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Background References:
  • Rivadeneira, F., et al. Nat. Genet. 41(11):1199-1206(2009)
  • Santra, M.K., et al. Nature 459(7247):722-725(2009)
  • Kumar, R., et al. Cancer Res. 65(24):11304-11313(2005)
  • Jin, J., et al. Genes Dev. 18(21):2573-2580(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This FBXO31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-338 amino acids from the Central region of human FBXO31.
NCBI Gene ID #:
79791
NCBI Official Name:
F-box only protein 31
NCBI Official Symbol:
FBXO31
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
61 kDa
Protein Accession #:
Q5XUX0
Protein GI Number:
146345419
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle
Swissprot #:
Q5XUX0
User NOte:
Optimal dilutions for each application to be determined by the researcher.