RARRES3 Antibody

ProSci
Product Code: PSI-60-161
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-161-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

Further Information

Additional Names:
Retinoic acid receptor responder protein 3, 311-, HRAS-like suppressor 4, HRSL4, RAR-responsive protein TIG3, Retinoid-inducible gene 1 protein, Tazarotene-induced gene 3 protein, RARRES3, RIG1, TIG3
Application Note:
For WB starting dilution is: 1:1000
Background:
Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator.
Background References:
  • Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Uyama, T., et al. Biochim. Biophys. Acta 1791(12):1114-1124(2009)
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RARRES3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-71 amino acids from the Central region of human RARRES3.
NCBI Gene ID #:
5920
NCBI Official Name:
Retinoic acid receptor responder protein 3
NCBI Official Symbol:
RARRES3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
18 kDa
Protein Accession #:
Q9UL19
Protein GI Number:
20140910
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle
Swissprot #:
Q9UL19
User NOte:
Optimal dilutions for each application to be determined by the researcher.