CCNB1 Antibody
| Code | Size | Price |
|---|
| PSI-55-622-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
G2/mitotic-specific cyclin-B1, CCNB1, CCNB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
The protein encoded by this gene is a regulatory protein
involved in mitosis. The gene product complexes with p34(cdc2) to
form the maturation-promoting factor (MPF). Two alternative
transcripts have been found, a constitutively expressed transcript
and a cell cycle-regulated transcript, that is expressed
predominantly during G2/M phase. The different transcripts result
from the use of alternate transcription initiation sites. [provided
by RefSeq].
Background References:
- Kreis, N.N., et al. Oncogene 29(41):5591-5603(2010)
- van Zon, W., et al. J. Cell Biol. 190(4):587-602(2010)
- Harley, M.E., et al. EMBO J. 29(14):2407-2420(2010)
- Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat, Zebrafish, Hamster, B
Immunogen:
This CCNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-268 amino acids from the Central region of human CCNB1.
NCBI Gene ID #:
891
NCBI Official Name:
G2/mitotic-specific cyclin-B1
NCBI Official Symbol:
CCNB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
P14635
Protein GI Number:
116176
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Cell Cycle
Swissprot #:
P14635
User NOte:
Optimal dilutions for each application to be determined by the researcher.