RNF43 Antibody
| Code | Size | Price |
|---|
| PSI-56-920-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
E3 ubiquitin-protein ligase RNF43, 632-, RING finger protein 43, RNF43
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
RNF43 is a HAP95 (AKAP8L; MIM 609475) binding ubiquitin
ligase that promotes cell growth and is upregulated in colon cancer
(Yagyu et al., 2004 [PubMed 15492824]; Sugiura et al., 2008 [PubMed
18313049]).
Background References:
- Low, S.K., et al. PLoS ONE(7), E11824 (2010) :
- Sugiura, T., et al. Exp. Cell Res. 314(7):1519-1528(2008)
- Uchida, N., et al. Clin. Cancer Res. 10(24):8577-8586(2004)
- Yagyu, R., et al. Int. J. Oncol. 25(5):1343-1348(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RNF43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 543-572 amino acids from the C-terminal region of human RNF43.
NCBI Gene ID #:
54894
NCBI Official Name:
E3 ubiquitin-protein ligase RNF43
NCBI Official Symbol:
RNF43
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
86 kDa
Protein Accession #:
Q68DV7
Protein GI Number:
74757361
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle
Swissprot #:
Q68DV7
User NOte:
Optimal dilutions for each application to be determined by the researcher.