ITIH5 Antibody
| Code | Size | Price |
|---|
| PSI-55-530-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Inter-alpha-trypsin inhibitor heavy chain H5, ITI heavy chain H5, ITI-HC5, Inter-alpha-inhibitor heavy chain 5, ITIH5, KIAA1953
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
This gene encodes a heavy chain component of one of the
inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins
are involved in extracellular matrix stabilization and in the
prevention of tumor metastasis. They are also structurally related
plasma serine protease inhibitors and are composed of a light chain
and varying numbers of heavy chains. This family member is thought
to function as a tumor suppressor in breast and thyroid cancers.
Alternative splicing results in multiple transcript variants.
Background References:
- Pita, J.M., et al. Br. J. Cancer 101(10):1782-1791(2009)
- Veeck, J., et al. Pathologe 29 SUPPL 2, 338-346 (2008) :
- Veeck, J., et al. Oncogene 27(6):865-876(2008)
- Hamm, A., et al. BMC Cancer 8, 25 (2008) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ITIH5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 578-606 amino acids from the C-terminal region of human ITIH5.
NCBI Gene ID #:
80760
NCBI Official Name:
Inter-alpha-trypsin inhibitor heavy chain H5
NCBI Official Symbol:
ITIH5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
105 kDa
Protein Accession #:
Q86UX2
Protein GI Number:
187609608
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle
Swissprot #:
Q86UX2
User NOte:
Optimal dilutions for each application to be determined by the researcher.