SUV39H1 Antibody
| Code | Size | Price |
|---|
| PSI-57-423-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Histone-lysine N-methyltransferase SUV39H1, Histone H3-K9 methyltransferase 1, H3-K9-HMTase 1, Lysine N-methyltransferase 1A, Position-effect variegation 3-9 homolog, Suppressor of variegation 3-9 homolog 1, Su(var)3-9 homolog 1, SUV39H1, KMT1A, SUV39H
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the suppressor of variegation 3-9
homolog family and encodes a protein with a chromodomain and a
C-terminal SET domain. This nuclear protein moves to the
centromeres during mitosis and functions as a histone
methyltransferase, methylating Lys-9 of histone H3. Overall, it
plays a vital role in heterochromatin organization, chromosome
segregation, and mitotic progression.
Background References:
- Chen, L., et al. EMBO J. 29(15):2538-2552(2010)
- Goyama, S., et al. Leukemia 24(1):81-88(2010)
- Cherrier, T., et al. Oncogene 28(38):3380-3389(2009)
- Li, Z., et al. J. Biol. Chem. 284(16):10361-10366(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SUV39H1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-108 amino acids from the N-terminal region of human SUV39H1.
NCBI Gene ID #:
6839
NCBI Official Name:
Histone-lysine N-methyltransferase SUV39H1
NCBI Official Symbol:
SUV39H1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
O43463
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,
Swissprot #:
O43463
User NOte:
Optimal dilutions for each application to be determined by the researcher.