HNF4A Antibody
| Code | Size | Price |
|---|
| PSI-61-499-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Hepatocyte nuclear factor 4-alpha, HNF-4-alpha, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, TCF-14, Transcription factor HNF-4, HNF4A, HNF4, NR2A1, TCF14
Application Note:
For WB starting dilution is: 1:1000
Background:
HNF4A is a nuclear transcription factor which binds DNA as a homodimer. This protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This protein may play a role in development of the liver, kidney, and intestines. Mutations in this protein have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I.
Background References:
- Sugai,M., Pathol. Int. 58 (11), 681-686 (2008)
- Lee,S.S., Hepatology 48 (2), 635-645 (2008)
- Guo,H., Biochem. J. 394 (PT 2), 379-387 (2006)
- Hong,Y.H., J. Biol. Chem. 278 (30), 27495-27501 (2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat, Xenopus
Immunogen:
This HNF4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-146 amino acids from human HNF4A.
NCBI Gene ID #:
3172
NCBI Official Name:
Hepatocyte nuclear factor 4-alpha
NCBI Official Symbol:
HNF4A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
P41235
Protein GI Number:
148886624
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Cell Cycle,Obesity,Signal Transduction
Swissprot #:
P41235
User NOte:
Optimal dilutions for each application to be determined by the researcher.