OSTM1 Antibody
| Code | Size | Price |
|---|
| PSI-59-814-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, GL
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that may be involved in the
degradation of G proteins via the ubiquitin-dependent proteasome
pathway. The encoded protein binds to members of subfamily A of the
regulator of the G-protein signaling (RGS) family through an
N-terminal leucine-rich region. This protein also has a central
RING finger-like domain and E3 ubiquitin ligase activity. This
protein is highly conserved from flies to humans. Defects in this
gene may cause the autosomal recessive, infantile malignant form of
osteopetrosis.
Background References:
- Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
- Mazzolari, E., et al. Am. J. Hematol. 84(8):473-479(2009)
- Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)
- Feigin, M.E., et al. Cell. Signal. 20(5):949-957(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This OSTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-321 amino acids from the C-terminal region of human OSTM1.
NCBI Gene ID #:
28962
NCBI Official Name:
Osteopetrosis-associated transmembrane protein 1
NCBI Official Symbol:
OSTM1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
Q86WC4
Protein GI Number:
51316434
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Cell Cycle,Signal Transduction
Swissprot #:
Q86WC4
User NOte:
Optimal dilutions for each application to be determined by the researcher.