SPINT1 Antibody

ProSci
Product Code: PSI-58-209
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-209-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in human placenta tissue lysates (35ug/lane).

Western blot analysis in human placenta tissue lysates (35ug/lane).

Further Information

Additional Names:
Kunitz-type protease inhibitor 1, Hepatocyte growth factor activator inhibitor type 1, HAI-1, SPINT1, HAI1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.
Background References:
  • Chen, Y.W., et al. J. Biol. Chem. 285(41):31755-31762(2010)
  • Kauppinen, J.M., et al. Cancer Epidemiol. Biomarkers Prev. 19(9):2133-2142(2010)
  • Nakamura, K., et al. Int. J. Oncol. 35(2):239-248(2009)
  • Wang, J.K., et al. Am. J. Physiol., Cell Physiol. 297 (2), C459-C470 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SPINT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-207 amino acids from the Central region of human SPINT1.
NCBI Gene ID #:
6692
NCBI Official Name:
Kunitz-type protease inhibitor 1
NCBI Official Symbol:
SPINT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
O43278
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Immunology
Swissprot #:
O43278
User NOte:
Optimal dilutions for each application to be determined by the researcher.