RNF5 Antibody
| Code | Size | Price |
|---|
| PSI-56-430-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
E3 ubiquitin-protein ligase RNF5, 632-, Protein G16, RING finger protein 5, Ram1 homolog, HsRma1, RNF5, G16, NG2, RMA1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene contains a RING finger,
which is a motif known to be involved in protein-protein
interactions. This protein is a membrane-bound ubiquitin ligase. It
can regulate cell motility by targeting paxillin ubiquitination and
altering the distribution and localization of paxillin in cytoplasm
and cell focal adhesions.
Background References:
- Barcellos, L.F., et al. PLoS Genet.(10), E1000696 (2009) :
- Tcherpakov, M., et al. J. Biol. Chem. 284(18):12099-12109(2009)
- Zhong, B., et al. Immunity 30(3):397-407(2009)
- McKinnon, E., et al. Diabetes Obes Metab 11 SUPPL 1, 92-100 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This RNF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-94 amino acids from the Central region of human RNF5.
NCBI Gene ID #:
6048
NCBI Official Name:
E3 ubiquitin-protein ligase RNF5
NCBI Official Symbol:
RNF5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
20 kDa
Protein Accession #:
Q99942
Protein GI Number:
74762702
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Immunology,
Swissprot #:
Q99942
User NOte:
Optimal dilutions for each application to be determined by the researcher.