KIT Antibody
| Code | Size | Price |
|---|
| PSI-60-079-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Mast/stem cell growth factor receptor Kit, SCFR, Piebald trait protein, PBT, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, CD117, KIT, SCFR
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes the human homolog of the proto-oncogene
c-kit. C-kit was first identified as the cellular homolog of the
feline sarcoma viral oncogene v-kit. This protein is a type 3
transmembrane receptor for MGF (mast cell growth factor, also known
as stem cell factor). Mutations in this gene are associated with
gastrointestinal stromal tumors, mast cell disease, acute
myelogenous lukemia, and piebaldism. Multiple transcript variants
encoding different isoforms have been found for this gene.
Background References:
- Molderings, G.J., et al. Immunogenetics 62 (11-12), 721-727 (2010) :
- Cheng, M., et al. Circ. Res. 107(9):1083-1093(2010)
- Chi, P., et al. Nature 467(7317):849-853(2010)
- Rossi, S., et al. Am. J. Surg. Pathol. 34(10):1480-1491(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 937-966 amino acids from the C-terminal region of human KIT.
NCBI Gene ID #:
3815
NCBI Official Name:
Mast/stem cell growth factor receptor Kit
NCBI Official Symbol:
KIT
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
110 kDa
Protein Accession #:
P10721
Protein GI Number:
125472
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Immunology,Neuroscience,Signal Transduction
Swissprot #:
P10721
User NOte:
Optimal dilutions for each application to be determined by the researcher.