SERPINE1 Antibody
| Code | Size | Price |
|---|
| PSI-56-733-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Plasminogen activator inhibitor 1, PAI, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1, SERPINE1, PAI1, PLANH1
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
This gene encodes a member of the serine proteinase
inhibitor (serpin) superfamily. This member is the principal
inhibitor of tissue plasminogen activator (tPA) and urokinase
(uPA), and hence is an inhibitor of fibrinolysis. Defects in this
gene are the cause of plasminogen activator inhibitor-1 deficiency
(PAI-1 deficiency), and high concentrations of the gene product are
associated with thrombophilia. Alternatively spliced transcript
variants encoding different isoforms have been found for this gene.
Background References:
- Ma, Z., et al. Biochem. Biophys. Res. Commun. 400(4):569-574(2010)
- Ince, D.A., et al. Genet Test Mol Biomarkers 14(5):643-647(2010)
- Bern, M.M., et al. Clin. Appl. Thromb. Hemost. 16(5):574-578(2010)
- Markl, B., et al.Surg Oncol 102(3):235-241(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SERPINE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-216 amino acids from the Central region of human SERPINE1.
NCBI Gene ID #:
5054
NCBI Official Name:
Plasminogen activator inhibitor 1
NCBI Official Symbol:
SERPINE1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
P05121
Protein GI Number:
129576
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Immunology,Obesity
Swissprot #:
P05121
User NOte:
Optimal dilutions for each application to be determined by the researcher.