CYBA Antibody
| Code | Size | Price |
|---|
| PSI-56-245-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cytochrome b-245 light chain, Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox, p22phox, CYBA
Application Note:
For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Background:
Cytochrome b is comprised of a light chain (alpha) and a
heavy chain (beta). This gene encodes the light, alpha subunit
which has been proposed as a primary component of the microbicidal
oxidase system of phagocytes. Mutations in this gene are associated
with autosomal recessive chronic granulomatous disease (CGD), that
is characterized by the failure of activated phagocytes to generate
superoxide, which is important for the microbicidal activity of
these cells.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Katakami, N., et al. Atherosclerosis 212(2):534-538(2010)
- Tu, Y.C., et al. Acta Pharmacol. Sin. 31(7):874-880(2010)
- Moreno, M.U., et al. Drug News Perspect. 23(5):316-324(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CYBA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-145 amino acids from the C-terminal region of human CYBA.
NCBI Gene ID #:
1535
NCBI Official Name:
Cytochrome b-245 light chain
NCBI Official Symbol:
CYBA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa
Protein Accession #:
P13498
Protein GI Number:
311033459
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Immunology,Obesity
Swissprot #:
P13498
User NOte:
Optimal dilutions for each application to be determined by the researcher.