ENG Antibody
| Code | Size | Price |
|---|
| PSI-55-726-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Endoglin, CD105, ENG, END
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
This gene encodes a homodimeric transmembrane protein
which is a major glycoprotein of the vascular endothelium. This
protein is a component of the transforming growth factor beta
receptor complex and it binds TGFB1 and TGFB3 with high affinity.
Mutations in this gene cause hereditary hemorrhagic telangiectasia,
also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant
multisystemic vascular dysplasia. Alternatively spliced transcript
variants encoding different isoforms have been found for this gene.
Background References:
- Lopez-Novoa, J.M., et al. Am. J. Physiol. Heart Circ. Physiol. 299 (4), H959-H974 (2010) :
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Zabaneh, D., et al. PLoS ONE(8), E11961 (2010) :
- Maynard, S.E., et al. Hypertens Pregnancy 29(3):330-341(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ENG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-294 amino acids from the Central region of human ENG.
NCBI Gene ID #:
2022
NCBI Official Name:
Endoglin
NCBI Official Symbol:
ENG
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
71 kDa
Protein Accession #:
P17813
Protein GI Number:
3041681
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Immunology,Signal Transduction
Swissprot #:
P17813
User NOte:
Optimal dilutions for each application to be determined by the researcher.