Mouse Mapk14 Antibody
| Code | Size | Price |
|---|
| PSI-58-339-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, CRK1, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Mapk14, Crk1, Csbp1, Csbp2
Application Note:
For WB starting dilution is: 1:1000
Background:
Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. Required in mid-fetal development for the growth of embryo-derived blood vessels in the labyrinth layer of the placenta. Also plays an essential role in developmental and stress-induced erythropoiesis, through regulation of EPO gene expression.
Background References:
- Pan, W.W., et al. J. Biol. Chem. 285(45):34348-34354(2010)
- Menon, M.B., et al. J. Biol. Chem. 285(43):33242-33251(2010)
- Chandrakesan, P., et al. J. Biol. Chem. 285(43):33485-33498(2010)
- Ferreiro, I., et al. J. Biol. Chem. 285(41):31819-31828(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This Mouse Mapk14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-53 amino acids from the N-terminal region of mouse Mapk14.
NCBI Gene ID #:
26416
NCBI Official Name:
Mitogen-activated protein kinase 14
NCBI Official Symbol:
Mapk14
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
P47811
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Immunology,Signal Transduction,
Swissprot #:
P47811
User NOte:
Optimal dilutions for each application to be determined by the researcher.