Kallikrein 3 Antibody
| Code | Size | Price |
|---|
| PSI-62-245-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Prostate-specific antigen, PSA, Gamma-seminoprotein, Seminin, Kallikrein-3, P-30 antigen, Semenogelase, KLK3, APS
Application Note:
For WB starting dilution is: 1:1000
Background:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK3 is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma.
Background References:
- Binnie, M.C., et al., Prostate 63(4):309-315 (2005).
- Habib, F.K., et al., Int. J. Cancer 114(2):190-194 (2005).
- Laidler, P., et al., Arch. Biochem. Biophys. 435(1):1-14 (2005).
- Dallas, S.L., et al., J. Cell. Physiol. 202(2):361-370 (2005).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Kallikrein 3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-250 amino acids from the C-terminal region of human Kallikrein 3.
NCBI Gene ID #:
354
NCBI Official Name:
Prostate-specific antigen
NCBI Official Symbol:
KLK3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
29 kDa
Protein Accession #:
P07288
Protein GI Number:
130989
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Cell Cycle,Neuroscience,Signal Transduction
Swissprot #:
P07288
User NOte:
Optimal dilutions for each application to be determined by the researcher.