CTSD Antibody
| Code | Size | Price |
|---|
| PSI-63-951-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cathepsin D, Cathepsin D light chain, Cathepsin D heavy chain, CTSD, CPSD
Application Note:
For WB starting dilution is: 1:1000
Background:
CTSD encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript.
Background References:
- Christensen, B., et al. J. Biol. Chem. 285(11):7929-7937(2010)
- Albayrak, O., et al. J. Gerontol.Biol. Sci. Med. Sci. 65(3):219-224(2010)
- Heinrich, M., et al. EMBO J. 18(19):5252-5263(1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CTSD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-408 amino acids from the C-terminal region of human CTSD.
NCBI Gene ID #:
1509
NCBI Official Name:
Cathepsin D
NCBI Official Symbol:
CTSD
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
P07339
Protein GI Number:
115717
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Cell Cycle,Neuroscience,Signal Transduction
Swissprot #:
P07339
User NOte:
Optimal dilutions for each application to be determined by the researcher.