WNT6 Antibody
| Code | Size | Price |
|---|
| PSI-58-564-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Protein Wnt-6, WNT6
Application Note:
For WB starting dilution is: 1:1000
Background:
The WNT gene family consists of structurally related genes
which encode secreted signaling proteins. These proteins have been
implicated in oncogenesis and in several developmental processes,
including regulation of cell fate and patterning during
embryogenesis. This gene is a member of the WNT gene family. It is
overexpressed in cervical cancer cell line and strongly coexpressed
with another family member, WNT10A, in colorectal cancer cell line.
The gene overexpression may play key roles in carcinogenesis. This
gene and the WNT10A gene are clustered in the chromosome 2q35
region. The protein encoded by this gene is 97% identical to the
mouse Wnt6 protein at the amino acid level.
Background References:
- Wang, C., et al.Endod 36(2):238-243(2010)
- Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
- Adaimy, L., et al. Am. J. Hum. Genet. 81(4):821-828(2007)
- Beaty, T.H., et al. Hum. Genet. 120(4):501-518(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This WNT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-201 amino acids from the Central region of human WNT6.
NCBI Gene ID #:
7475
NCBI Official Name:
Protein Wnt-6
NCBI Official Symbol:
WNT6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa
Protein Accession #:
Q9Y6F9
Protein GI Number:
14424016
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Neuroscience,Signal Transduction
Swissprot #:
Q9Y6F9
User NOte:
Optimal dilutions for each application to be determined by the researcher.