RORC Antibody
| Code | Size | Price |
|---|
| PSI-57-272-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, RAR-related orphan receptor C, Retinoid-related orphan receptor-gamma, RORC, NR1F3, RORG, RZRG
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a DNA-binding
transcription factor and is a member of the NR1 subfamily of
nuclear hormone receptors. The specific functions of this protein
are not known; however, studies of a similar gene in mice have
shown that this gene may be essential for lymphoid organogenesis
and may play an important regulatory role in thymopoiesis. In
addition, studies in mice suggest that the protein encoded by this
gene may inhibit the expression of Fas ligand and IL2. Two
transcript variants encoding different isoforms have been found for
this gene.
Background References:
- Wang, Y., et al. Biochim. Biophys. Acta 1801(8):917-923(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Burgler, S., et al. J. Immunol. 184(11):6161-6169(2010)
- Jin, L., et al. Mol. Endocrinol. 24(5):923-929(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RORC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human RORC.
NCBI Gene ID #:
6097
NCBI Official Name:
Nuclear receptor ROR-gamma
NCBI Official Symbol:
RORC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
P51449
Protein GI Number:
49066040
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Neuroscience,Signal Transduction
Swissprot #:
P51449
User NOte:
Optimal dilutions for each application to be determined by the researcher.