HMGA2 Antibody
| Code | Size | Price |
|---|
| PSI-61-900-400ul | 400ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
High mobility group protein HMGI-C, High mobility group AT-hook protein 2, HMGA2, HMGIC
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
This gene encodes a protein that belongs to the
non-histone chromosomal high mobility group (HMG) protein family.
HMG proteins function as architectural factors and are essential
components of the enhancesome. This protein contains structural
DNA-binding domains and may act as a transcriptional regulating
factor. Identification of the deletion, amplification, and
rearrangement of this gene that are associated with myxoid
liposarcoma suggests a role in adipogenesis and mesenchymal
differentiation. A gene knock out study of the mouse counterpart
demonstrated that this gene is involved in diet-induced obesity.
Alternate transcriptional splice variants, encoding different
isoforms, have been characterized.
Background References:
- Mu, G., et al. Hum. Pathol. 41(4):493-502(2010)
- Pillas, D., et al. PLoS Genet.(2), E1000856 (2010) :
- Yang, T.L., et al. Ann. Hum. Genet. 74(1):11-16(2010)
- Wei, J.J., et al. Am. J. Surg. Pathol. 34(1):18-26(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This HMGA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the C-terminal region of human HMGA2.
NCBI Gene ID #:
8091
NCBI Official Name:
High mobility group protein HMGI-C
NCBI Official Symbol:
HMGA2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
12 kDa
Protein Accession #:
P52926
Protein GI Number:
1708263
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Neuroscience,Signal Transduction
Swissprot #:
P52926
User NOte:
Optimal dilutions for each application to be determined by the researcher.