CSTA Antibody
Code | Size | Price |
---|
PSI-57-666-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Images
Documents
Further Information
Additional Names:
Cystatin-A, Cystatin-AS, Stefin-A, Cystatin-A, N-terminally processed, CSTA, STF1, STFA
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The cystatin superfamily encompasses proteins that contain
multiple cystatin-like sequences. Some of the members are active
cysteine protease inhibitors, while others have lost or perhaps
never acquired this inhibitory activity. There are three inhibitory
families in the superfamily, including the type 1 cystatins
(stefins), type 2 cystatins, and kininogens. This gene encodes a
stefin that functions as a cysteine protease inhibitor, forming
tight complexes with papain and the cathepsins B, H, and L. The
protein is one of the precursor proteins of cornified cell envelope
in keratinocytes and plays a role in epidermal development and
maintenance. Stefins have been proposed as prognostic and
diagnostic tools for cancer.
Background References:
- O'Seaghdha, C.M., et al. Hum. Mol. Genet. 19(21):4296-4303(2010)
- Kestenbaum, B., et al. J. Am. Soc. Nephrol. 21(7):1223-1232(2010)
- Takai, T., et al. J. Immunol. 183(12):7958-7965(2009)
- Vasilopoulos, Y., et al. Eur. J. Hum. Genet. 16(8):1002-1009(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CSTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the C-terminal region of human CSTA.
NCBI Gene ID #:
1475
NCBI Official Name:
Cystatin-A
NCBI Official Symbol:
CSTA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
11 kDa
Protein Accession #:
P01040
Protein GI Number:
118177
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Neuroscience,Signal Transduction
Swissprot #:
P01040
User NOte:
Optimal dilutions for each application to be determined by the researcher.