HMOX2 Antibody

ProSci
Product Code: PSI-60-469
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-469-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Jurkat cell line lysates (35ug/lane).

Western blot analysis in Jurkat cell line lysates (35ug/lane).

Further Information

Additional Names:
Heme oxygenase 2, HO-2, HMOX2, HO2
Application Note:
For WB starting dilution is: 1:1000
Background:
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Alternative splice variants encoding the same protein have been identified at this locus.
Background References:
  • Abdel Aziz, M.T., et al. Andrologia 42(4):236-241(2010)
  • Wang, Y., et al. J. Hum. Genet. 55(8):490-494(2010)
  • He, J.Z., et al. J. Biol. Chem. 285(13):9452-9461(2010)
  • Zhong, J.L., et al. Free Radic. Biol. Med. 48(2):196-206(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Rat
Immunogen:
This HMOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human HMOX2.
NCBI Gene ID #:
3163
NCBI Official Name:
Heme oxygenase 2
NCBI Official Symbol:
HMOX2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
36 kDa
Protein Accession #:
P30519
Protein GI Number:
1170328
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Obesity
Swissprot #:
P30519
User NOte:
Optimal dilutions for each application to be determined by the researcher.