GGPS1 Antibody
Code | Size | Price |
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PSI-58-734-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Geranylgeranyl pyrophosphate synthase, GGPP synthase, GGPPSase, 251-, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase, GGPS1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the prenyltransferase family and
encodes a protein with geranylgeranyl diphosphate (GGPP) synthase
activity. The enzyme catalyzes the synthesis of GGPP from farnesyl
diphosphate and isopentenyl diphosphate. GGPP is an important
molecule responsible for the C20-prenylation of proteins and for
the regulation of a nuclear hormone receptor. Alternate
transcriptional splice variants, both protein-coding and
non-protein-coding, have been found for this gene. [provided by
RefSeq].
Background References:
- Choi, H.J., et al. Yonsei Med. J. 51(2):231-238(2010)
- Raz, T., et al. Blood 110(6):2102-2109(2007)
- Miyagi, Y., et al. J. Biochem. 142(3):377-381(2007)
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This GGPS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-202 amino acids from the Central region of human GGPS1.
NCBI Gene ID #:
9453
NCBI Official Name:
Geranylgeranyl pyrophosphate synthase
NCBI Official Symbol:
GGPS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
35 kDa
Protein Accession #:
O95749
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Obesity
Swissprot #:
O95749
User NOte:
Optimal dilutions for each application to be determined by the researcher.