TSH-alpha Antibody

ProSci
Product Code: PSI-56-122
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-122-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in HepG2 cell line lysates (35ug/lane).

Western blot analysis in HepG2 cell line lysates (35ug/lane).

Further Information

Additional Names:
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, CG-alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain, CGA
Application Note:
For WB starting dilution is: 1:1000
Background:
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family.
Background References:
  • Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010)
  • Panicker, V., et al. Am. J. Hum. Genet. 87(3):430-435(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Robinson, N., et al. Clin. Lab. 56 (5-6), 197-206 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TSH-alpha antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-103 amino acids from the C-terminal region of human TSH-alpha.
NCBI Gene ID #:
1081
NCBI Official Name:
Glycoprotein hormones alpha chain
NCBI Official Symbol:
CGA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
13 kDa
Protein Accession #:
P01215
Protein GI Number:
121312
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Obesity,Neuroscience,Signal Transduction
Swissprot #:
P01215
User NOte:
Optimal dilutions for each application to be determined by the researcher.