CGB/hCG-Beta Antibody

ProSci
Product Code: PSI-57-851
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-851-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the detected the CGB/HCG-Beta protein (arrow).

Western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the detected the CGB/HCG-Beta protein (arrow).

Further Information

Additional Names:
Choriogonadotropin subunit beta, CG-beta, Chorionic gonadotrophin chain beta, CGB, CGB3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.
Background References:
  • Cole, L.A. Placenta 31(8):653-664(2010) Ra, Y.J., et al. Interact Cardiovasc Thorac Surg 11(1):114-116(2010) Verma, B., et al. J. Immunol. 184(4):2156-2165(2010) Handschuh, K., et al. Placenta 30(12):1016-1022(2009) Reisenbichler, E.S., et al. Breast15(5):527-530(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CGB/hCG-Beta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-90 amino acids from the Central region of human CGB/hCG-Beta.
NCBI Gene ID #:
1082, 93659, 94027, 94115
NCBI Official Name:
Choriogonadotropin subunit beta
NCBI Official Symbol:
CGB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
18 kDa
Protein Accession #:
P01233
Protein GI Number:
116184
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Obesity,Signal Transduction
Swissprot #:
P01233
User NOte:
Optimal dilutions for each application to be determined by the researcher.