VEGFA Antibody
| Code | Size | Price |
|---|
| PSI-56-265-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGFA, VEGF
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the PDGF/VEGF growth factor
family and encodes a protein that is often found as a disulfide
linked homodimer. This protein is a glycosylated mitogen that
specifically acts on endothelial cells and has various effects,
including mediating increased vascular permeability, inducing
angiogenesis, vasculogenesis and endothelial cell growth, promoting
cell migration, and inhibiting apoptosis. Elevated levels of this
protein is linked to POEMS syndrome, also known as Crow-Fukase
syndrome. Mutations in this gene have been associated with
proliferative and nonproliferative diabetic retinopathy.
Alternatively spliced transcript variants, encoding either freely
secreted or cell-associated isoforms, have been characterized.
There is also evidence for the use of non-AUG (CUG) translation
initiation sites upstream of, and in-frame with the first AUG,
leading to additional isoforms.
Background References:
- Shrivastava-Ranjan, P., et al. J. Virol. 84(21):11227-11234(2010)
- Kim, Y.H., et al. Gynecol. Oncol. 119(2):232-236(2010)
- Yang, Y., et al. Exp. Biol. Med. (Maywood) 235(10):1204-1211(2010)
- Huez, I., et al. Mol. Endocrinol. 15(12):2197-2210(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This VEGFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the Central region of human VEGFA.
NCBI Gene ID #:
7422
NCBI Official Name:
Vascular endothelial growth factor A
NCBI Official Symbol:
VEGFA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa
Protein Accession #:
P15692
Protein GI Number:
17380528
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Obesity,Signal Transduction
Swissprot #:
P15692
User NOte:
Optimal dilutions for each application to be determined by the researcher.