PRKAR1B Antibody

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ProSci
Product Code: PSI-59-017
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-017-400ul400ul£626.00
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in CEM cell line lysates (35ug/lane).
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Western blot analysis in CEM cell line lysates (35ug/lane).

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Further Information

Additional Names:
cAMP-dependent protein kinase type I-beta regulatory subunit, PRKAR1B
Application Note:
For WB starting dilution is: 1:1000
Background:
Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.[supplied by OMIM].
Background References:
  • Silva, L.K., et al. Eur. J. Hum. Genet. (2010) In press :
  • Liu, Y.J., et al. Obesity (Silver Spring) (2010) In press :
  • Zhan, X., et al. Anal. Biochem. 354(2):279-289(2006)
  • Gullingsrud, J., et al. Structure 14(1):141-149(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PRKAR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the N-terminal region of human PRKAR1B.
NCBI Gene ID #:
5575
NCBI Official Name:
cAMP-dependent protein kinase type I-beta regulatory subunit
NCBI Official Symbol:
PRKAR1B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
P31321
Protein GI Number:
229463042
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Obesity,Signal Transduction
Swissprot #:
P31321
User NOte:
Optimal dilutions for each application to be determined by the researcher.