BAG2 Antibody
| Code | Size | Price |
|---|
| PSI-57-448-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
BAG family molecular chaperone regulator 2, BAG-2, Bcl-2-associated athanogene 2, BAG2
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
BAG proteins compete with Hip for binding to the
Hsc70/Hsp70 ATPase domain and promote substrate release. All the
BAG proteins have an approximately 45-amino acid BAG domain near
the C terminus but differ markedly in their N-terminal regions. The
predicted BAG2 protein contains 211 amino acids. The BAG domains of
BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase
domain in vitro and in mammalian cells. All 3 proteins bind with
high affinity to the ATPase domain of Hsc70 and inhibit its
chaperone activity in a Hip-repressible manner. [provided by
RefSeq].
Background References:
- Arndt, V., et al. Mol. Biol. Cell 16(12):5891-5900(2005)
- Dai, Q., et al. J. Biol. Chem. 280(46):38673-38681(2005)
- Ueda, K., et al. J. Biol. Chem. 279(40):41815-41821(2004)
- Ueda, K., et al. J. Biol. Chem. 279(40):41815-41821(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This BAG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the C-terminal region of human BAG2.
NCBI Gene ID #:
9532
NCBI Official Name:
BAG family molecular chaperone regulator 2
NCBI Official Symbol:
BAG2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
24 kDa
Protein Accession #:
O95816
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Obesity,Signal Transduction
Swissprot #:
O95816
User NOte:
Optimal dilutions for each application to be determined by the researcher.