TGF Beta 2 Antibody

ProSci
Product Code: PSI-57-975
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-975-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Raji cell line lysates (35ug/lane).
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Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with TGFB2 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Western blot analysis in Raji cell line lysates (35ug/lane).
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with TGFB2 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Further Information

Additional Names:
Transforming growth factor beta-2, TGF-beta-2, BSC-1 cell growth inhibitor, Cetermin, Glioblastoma-derived T-cell suppressor factor, G-TSF, Polyergin, Latency-associated peptide, LAP, TGFB2
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50
Background:
Transforming growth factor-beta 2 (TGF-?2) is a cytokine that performs many cellular functions and has a vital role during embryonic development. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. There are two named isoforms of this protein, created by alternative splicing of the same gene.
Background References:
  • Hatsushika,K., Clin. Exp. Allergy 37 (8), 1165-1174 (2007) Jimi,S., Int. J. Oncol. 31 (2), 397-404 (2007) Ito,T., Biochem. Biophys. Res. Commun. 359 (1), 108-114 (2007) Yao,K., Mol. Vis. 13, 1769-1776 (2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TGF Beta 2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the C-terminal region of human TGF Beta 2.
NCBI Gene ID #:
7042
NCBI Official Name:
Transforming growth factor beta-2
NCBI Official Symbol:
TGFB2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
P61812
Protein GI Number:
48429157
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Cell Cycle,Obesity,Signal Transduction
Swissprot #:
P61812
User NOte:
Optimal dilutions for each application to be determined by the researcher.