IGFBP3 Antibody
| Code | Size | Price |
|---|
| PSI-63-090-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Insulin-like growth factor-binding protein 3, IBP-3, IGF-binding protein 3, IGFBP-3, IGFBP3, IBP3
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors.
Background References:
- Muzumdar,R.H., Diabetes 55 (10), 2788-2796 (2006)
- Novosyadlyy,R., Growth Horm. IGF Res. 15 (5), 313-323 (2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This IGFBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-193 amino acids from the N-terminal region of human IGFBP3.
NCBI Gene ID #:
3486
NCBI Official Name:
Insulin-like growth factor-binding protein 3
NCBI Official Symbol:
IGFBP3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
P17936
Protein GI Number:
146327827
Purification:
This antibody is purified through a protein G column, followed by dialysis against PBS.
Research Area:
Cancer,Cell Cycle,Obesity,Signal Transduction
Swissprot #:
P17936
User NOte:
Optimal dilutions for each application to be determined by the researcher.