PRDX6 Antibody
| Code | Size | Price |
|---|
| PSI-61-606-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Peroxiredoxin-6, 1-Cys peroxiredoxin, 1-Cys PRX, 24 kDa protein, Acidic calcium-independent phospholipase A2, aiPLA2, 311-, Antioxidant protein 2, Liver 2D page spot 40, Non-selenium glutathione peroxidase, NSGPx, Red blood cells page spot 12, PRDX6, AOP2, KIAA0106
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Background:
PRDX6 is a member of the
thiol-specific antioxidant protein family. This protein is a
bifunctional enzyme with two distinct active sites. It is involved
in redox regulation of the cell; it can reduce H(2)O(2) and short
chain organic, fatty acid, and phospholipid hydroperoxides. It may
play a role in the regulation of phospholipid turnover as well as
in protection against oxidative injury.
Background References:
- Davila, S., et al. Genes Immun. (2010) In press :
- Kubo, E., et al. Am. J. Physiol., Cell Physiol. 298 (2), C342-C354 (2010) :
- Sorokina, E.M., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 297 (5), L871-L880 (2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Rat
Immunogen:
This PRDX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the Central region of human PRDX6.
NCBI Gene ID #:
9588
NCBI Official Name:
Peroxiredoxin-6
NCBI Official Symbol:
PRDX6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
P30041
Protein GI Number:
1718024
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Obesity,Signal Transduction
Swissprot #:
P30041
User NOte:
Optimal dilutions for each application to be determined by the researcher.