KLK10 Antibody

ProSci
Product Code: PSI-57-815
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-815-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in HepG2 cell line lysates (35ug/lane).
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Western blot analysis of KLK10 using rabbit polyclonal KLK10 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the KLK10 gene.

Western blot analysis in HepG2 cell line lysates (35ug/lane).
Western blot analysis of KLK10 using rabbit polyclonal KLK10 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the KLK10 gene.

Further Information

Additional Names:
Kallikrein-10, 3421-, Normal epithelial cell-specific 1, Protease serine-like 1, KLK10, NES1, PRSSL1
Application Note:
For WB starting dilution is: 1:1000
Background:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq].
Background References:
  • Batra, J., et al. Int. J. Gynecol. Cancer 20(4):529-536(2010)
  • Klein, R.J., et al. Cancer Prev Res (Phila) 3(5):611-619(2010)
  • Papageorgis, P., et al. Cancer Res. 70(3):968-978(2010)
  • Lu, C.Y., et al. Genes Chromosomes Cancer 48(12):1057-1068(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KLK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from the N-terminal region of human KLK10.
NCBI Gene ID #:
5655
NCBI Official Name:
Kallikrein-10
NCBI Official Symbol:
KLK10
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
30 kDa
Protein Accession #:
O43240
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
O43240
User NOte:
Optimal dilutions for each application to be determined by the researcher.