MMP26 Antibody
| Code | Size | Price |
|---|
| PSI-60-765-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Matrix metalloproteinase-26, MMP-26, 3424-, Endometase, Matrilysin-2, MMP26
Application Note:
For WB starting dilution is: 1:1000
Background:
Proteins of the matrix metalloproteinase (MMP) family are
involved in the breakdown of extracellular matrix in normal
physiological processes, such as embryonic development,
reproduction, and tissue remodeling, as well as in disease
processes, such as arthritis and metastasis. Most MMP's are
secreted as inactive proproteins which are activated when cleaved
by extracellular proteinases. The encoded protein degrades type IV
collagen, fibronectin, fibrinogen, casein, vitronectin, alpha
1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth
factor-binding protein 1, and activates MMP9 by cleavage. The
protein differs from most MMP family members in that it lacks a
conserved C-terminal protein domain.
Background References:
- de Amorim, R.F., et al. Acta Odontol. Scand. 68(4):228-231(2010)
- Ban, J.Y., et al. Life Sci. 86 (19-20), 756-759 (2010) :
- Deng, Y., et al. Oncol. Rep. 23(1):69-78(2010)
- Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MMP26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 amino acids from the Central region of human MMP26.
NCBI Gene ID #:
56547
NCBI Official Name:
Matrix metalloproteinase-26
NCBI Official Symbol:
MMP26
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
30 kDa
Protein Accession #:
Q9NRE1
Protein GI Number:
13629493
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
Q9NRE1
User NOte:
Optimal dilutions for each application to be determined by the researcher.