EGF Antibody
| Code | Size | Price |
|---|
| PSI-60-331-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Pro-epidermal growth factor, EGF, Epidermal growth factor, Urogastrone, EGF
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the epidermal growth factor
superfamily. The encoded protein is synthesized as a large
precursor molecule that is proteolytically cleaved to generate the
53-amino acid epidermal growth factor peptide. This protein acts a
potent mitogenic factor that plays an important role in the growth,
proliferation and differentiation of numerous cell types. This
protein acts by binding the high affinity cell surface receptor,
epidermal growth factor receptor. Defects in this gene are the
cause of hypomagnesemia type 4. Dysregulation of this gene has been
associated with the growth and progression of certain cancers.
Alternate splicing results in multiple transcript variants.
Background References:
- de Diesbach, M.T., et al. Exp. Cell Res. 316(19):3239-3253(2010)
- Xu, Z., et al. Biochem. Biophys. Res. Commun. 401(3):376-381(2010)
- Lupien, M., et al. Genes Dev. 24(19):2219-2227(2010)
- Hommel, U., et al. J. Mol. Biol. 227(1):271-282(1992)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This EGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 940-967 amino acids from the C-terminal region of human EGF.
NCBI Gene ID #:
1950
NCBI Official Name:
Pro-epidermal growth factor
NCBI Official Symbol:
EGF
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
134 kDa
Protein Accession #:
P01133
Protein GI Number:
251757262
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
P01133
User NOte:
Optimal dilutions for each application to be determined by the researcher.