TPBG Antibody

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ProSci
Product Code: PSI-58-957
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-957-400ul400ul£626.00
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A2058 cell line lysates (35ug/lane).
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Western blot analysis in A2058 cell line lysates (35ug/lane).

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Further Information

Additional Names:
Trophoblast glycoprotein, 5T4 oncofetal antigen, 5T4 oncofetal trophoblast glycoprotein, 5T4 oncotrophoblast glycoprotein, M6P1, Wnt-activated inhibitory factor 1, WAIF1, TPBG, 5T4
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq].
Background References:
  • Elkord, E., et al. J. Immunother. 31(9):820-829(2008)
  • Shingler, W.H., et al. Int. Immunol. 20(8):1057-1066(2008)
  • Okazaki, S., et al. Obstet Gynecol 110(5):1130-1136(2007)
  • Ward, C.M., et al. Exp. Cell Res. 312(10):1713-1726(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TPBG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-197 amino acids from the Central region of human TPBG.
NCBI Gene ID #:
7162
NCBI Official Name:
Trophoblast glycoprotein
NCBI Official Symbol:
TPBG
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
Protein Accession #:
Q13641
Protein GI Number:
73621980
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
Q13641
User NOte:
Optimal dilutions for each application to be determined by the researcher.