ADAM11 Antibody
| Code | Size | Price |
|---|
| PSI-57-458-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Disintegrin and metalloproteinase domain-containing protein 11, ADAM 11, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein, MDC, ADAM11, MDC
Application Note:
For WB starting dilution is: 1:500
Background:
This gene encodes a member of the ADAM (a disintegrin and
metalloprotease) protein family. Members of this family are
membrane-anchored proteins structurally related to snake venom
disintegrins, and have been implicated in a variety of biological
processes involving cell-cell and cell-matrix interactions,
including fertilization, muscle development, and neurogenesis. This
gene represents a candidate tumor supressor gene for human breast
cancer based on its location within a minimal region of chromosome
17q21 previously defined by tumor deletion mapping. [provided by
RefSeq].
Background References:
- Fu, G.K., et al. Genomics 84(1):205-210(2004)
- Hillman, R.T., et al. Genome Biol.(2), R8 (2004) :
- Shea, S.H., et al. Behav. Genet. 31(2):231-239(2001)
- Sagane, K., et al. Biochem. J. 334 (PT 1), 93-98 (1998) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ADAM11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-228 amino acids from the N-terminal region of human ADAM11.
NCBI Gene ID #:
4185
NCBI Official Name:
Disintegrin and metalloproteinase domain-containing protein 11
NCBI Official Symbol:
ADAM11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
83 kDa
Protein Accession #:
O75078
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
O75078
User NOte:
Optimal dilutions for each application to be determined by the researcher.