EpCAM Antibody
| Code | Size | Price |
|---|
| PSI-59-656-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Epithelial cell adhesion molecule, Ep-CAM, Adenocarcinoma-associated antigen, Cell surface glycoprotein Trop-1, Epithelial cell surface antigen, Epithelial glycoprotein, EGP, Epithelial glycoprotein 314, EGP314, hEGP314, KS 1/4 antigen, KSA, Major gastrointestinal tumor-associated protein GA733-2, Tumor-associated calcium signal transducer 1, CD326, EPCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a carcinoma-associated antigen and is a
member of a family that includes at least two type I membrane
proteins. This antigen is expressed on most normal epithelial cells
and gastrointestinal carcinomas and functions as a homotypic
calcium-independent cell adhesion molecule. The antigen is being
used as a target for immunotherapy treatment of human carcinomas.
Mutations in this gene result in congenital tufting enteropathy.
Background References:
- Kimura, O., et al. Cancer Sci. 101(10):2145-2155(2010)
- Jiang, L., et al. Breast Cancer Res. Treat. (2010) In press :
- Lugli, A., et al. Br. J. Cancer 103(3):382-390(2010)
- Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This EpCAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-229 amino acids from the C-terminal region of human EpCAM.
NCBI Gene ID #:
4072
NCBI Official Name:
Epithelial cell adhesion molecule
NCBI Official Symbol:
EPCAM
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
35 kDa
Protein Accession #:
P16422
Protein GI Number:
160266056
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
P16422
User NOte:
Optimal dilutions for each application to be determined by the researcher.