HOXB8 Antibody
| Code | Size | Price |
|---|
| PSI-58-305-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Homeobox protein Hox-B8, Homeobox protein Hox-24, Homeobox protein Hox-2D, HOXB8, HOX2D
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the Antp homeobox family and
encodes a nuclear protein with a homeobox DNA-binding domain. It is
included in a cluster of homeobox B genes located on chromosome 17.
The encoded protein functions as a sequence-specific transcription
factor that is involved in development. Increased expression of
this gene is associated with colorectal cancer. Mice that have had
the murine ortholog of this gene knocked out exhibit an excessive
pathologic grooming behavior. This behavior is similar to the
behavior of humans suffering from the obsessive-compulsive spectrum
disorder trichotillomania.
Background References:
- Kosaki, K., et al. Teratology 65(2):50-62(2002)
- Greer, J.M., et al. Neuron 33(1):23-34(2002)
- Knoepfler, P.S., et al. Oncogene 20(39):5440-5448(2001)
- Fujino, T., et al. Exp. Hematol. 29(7):856-863(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HOXB8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-243 amino acids from the C-terminal region of human HOXB8.
NCBI Gene ID #:
3218
NCBI Official Name:
Homeobox protein Hox-B8
NCBI Official Symbol:
HOXB8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
P17481
Protein GI Number:
20141506
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
P17481
User NOte:
Optimal dilutions for each application to be determined by the researcher.