MLL5 Antibody
Code | Size | Price |
---|
PSI-57-534-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Images
Documents
Further Information
Additional Names:
Histone-lysine N-methyltransferase 2E, Lysine N-methyltransferase 2E, Myeloid/lymphoid or mixed-lineage leukemia protein 5, KMT2E, MLL5
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the myeloid/lymphoid or
mixed-lineage leukemia (MLL) family and encodes a protein with an
N-terminal PHD zinc finger and a central SET domain. Overexpression
of the protein inhibits cell cycle progression. Alternate
transcriptional splice variants have been characterized. [provided
by RefSeq].
Background References:
- Liu, J., et al. J. Biol. Chem. 285(27):20904-20914(2010)
- Fujiki, R., et al. Nature 459(7245):455-459(2009)
- Cheng, F., et al. Int. J. Biochem. Cell Biol. 40(11):2472-2481(2008)
- Sun, X.J., et al. PLoS ONE(1), E1499 (2008) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This MLL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the N-terminal region of human MLL5.
NCBI Gene ID #:
55904
NCBI Official Name:
Histone-lysine N-methyltransferase 2E
NCBI Official Symbol:
KMT2E
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
205 kDa
Protein Accession #:
Q8IZD2
Protein GI Number:
74723669
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
Q8IZD2
User NOte:
Optimal dilutions for each application to be determined by the researcher.