DND1 Antibody

ProSci
Product Code: PSI-58-546
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-546-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Hela cell line lysates (35ug/lane).

Western blot analysis in Hela cell line lysates (35ug/lane).

Further Information

Additional Names:
Dead end protein homolog 1, RNA-binding motif, single-stranded-interacting protein 4, DND1, RBMS4
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Reduced expression of this gene has been implicated in tongue squamous cell carcinoma. Two pseudogenes of this gene are located on the long arm of chromosome 17.
Background References:
  • Liu, X., et al. FEBS Lett. 584(18):4115-4120(2010)
  • Sijmons, R.H., et al. Fam. Cancer 9(3):439-442(2010)
  • Kedde, M., et al. Cell Cycle 7(7):899-903(2008)
  • Linger, R., et al. Genes Chromosomes Cancer 47(3):247-252(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the Central region of human DND1.
NCBI Gene ID #:
373863
NCBI Official Name:
Dead end protein homolog 1
NCBI Official Symbol:
DND1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
Q8IYX4
Protein GI Number:
60389799
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
Q8IYX4
User NOte:
Optimal dilutions for each application to be determined by the researcher.