PODXL Antibody
| Code | Size | Price |
|---|
| PSI-60-255-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Podocalyxin, GCTM-2 antigen, Gp200, Podocalyxin-like protein 1, PC, PCLP-1, PODXL, PCLP, PCLP1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the sialomucin protein
family. The encoded protein was originally identified as an
important component of glomerular podocytes. Podocytes are highly
differentiated epithelial cells with interdigitating foot processes
covering the outer aspect of the glomerular basement membrane.
Other biological activities of the encoded protein include: binding
in a membrane protein complex with Na+/H+ exchanger regulatory
factor to intracellular cytoskeletal elements, playing a role in
hematopoetic cell differentiation, and being expressed in vascular
endothelium cells and binding to L-selectin.
Background References:
- Schopperle, W.M., et al. Biochem. Biophys. Res. Commun. 398(3):372-376(2010)
- Hsu, Y.H., et al. Am. J. Pathol. 176(6):3050-3061(2010)
- Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
- Drossopoulou, G.I., et al. Am. J. Physiol. Renal Physiol. 297 (3), F594-F603 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PODXL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-439 amino acids from the C-terminal region of human PODXL.
NCBI Gene ID #:
5420
NCBI Official Name:
Podocalyxin
NCBI Official Symbol:
PODXL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
O00592
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
O00592
User NOte:
Optimal dilutions for each application to be determined by the researcher.