PLZF Antibody

ProSci
Product Code: PSI-62-387
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-62-387-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of PLZF Antibody in 293, K562 cell line lysates (35ug/lane)

Western blot analysis of PLZF Antibody in 293, K562 cell line lysates (35ug/lane)

Further Information

Additional Names:
Zinc finger and BTB domain-containing protein 16, Promyelocytic leukemia zinc finger protein, Zinc finger protein 145, Zinc finger protein PLZF, ZBTB16, PLZF, ZNF145
Application Note:
For WB starting dilution is: 1:1000
Background:
PLZF is a member of the Krueppel C2H2-type zinc-finger protein family and a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL).
Background References:
  • Shi,J., Int. J. Cancer 125 (7), 1558-1565 (2009)
  • Doulatov,S., Genes Dev. 23 (17), 2076-2087 (2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PLZF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 637-666 amino acids from the C-terminal region of human PLZF.
NCBI Gene ID #:
7704
NCBI Official Name:
Zinc finger and BTB domain-containing protein 16
NCBI Official Symbol:
ZBTB16
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
74 kDa
Protein Accession #:
Q05516
Protein GI Number:
90109930
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
Q05516
User NOte:
Optimal dilutions for each application to be determined by the researcher.