CDKN3 Antibody
| Code | Size | Price |
|---|
| PSI-60-846-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cyclin-dependent kinase inhibitor 3, CDK2-associated dual-specificity phosphatase, Cyclin-dependent kinase interactor 1, Cyclin-dependent kinase-interacting protein 2, Kinase-associated phosphatase, CDKN3, CDI1, CIP2, KAP
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to the dual
specificity protein phosphatase family. It was identified as a
cyclin-dependent kinase inhibitor, and has been shown to interact
with, and dephosphorylate CDK2 kinase, thus prevent the activation
of CDK2 kinase. This gene was reported to be deleted, mutated, or
overexpressed in several kinds of cancers. Alternatively spliced
transcript variants encoding different isoforms have been found for
this gene.
Background References:
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Jiang, R., et al. Int. J. Cancer 126(5):1263-1274(2010)
- Okamoto, K., et al. Biochem. Biophys. Res. Commun. 351(1):216-222(2006)
- Hsieh, M.J., et al. Biochem. Biophys. Res. Commun. 349(2):573-581(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CDKN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the N-terminal region of human CDKN3.
NCBI Gene ID #:
1033
NCBI Official Name:
Cyclin-dependent kinase inhibitor 3
NCBI Official Symbol:
CDKN3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
24 kDa
Protein Accession #:
Q16667
Protein GI Number:
2499769
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
Q16667
User NOte:
Optimal dilutions for each application to be determined by the researcher.