CDCA4 Antibody
| Code | Size | Price |
|---|
| PSI-58-624-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cell division cycle-associated protein 4, Hematopoietic progenitor protein, CDCA4, HEPP
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that belongs to the E2F family
of transcription factors. This protein regulates E2F-dependent
transcriptional activation and cell proliferation, mainly through
the E2F/retinoblastoma protein pathway. It also functions in the
regulaton of JUN oncogene expression. This protein shows
distinctive nuclear-mitotic apparatus distribution, it is involved
in spindle organization from prometaphase, and may also play a role
as a midzone factor involved in chromosome segregation or
cytokinesis. Two alternatively spliced transcript variants encoding
the same protein have been noted for this gene. Two pseudogenes
have also been identified on chromosome 1.
Background References:
- Tategu, M., et al. Biochimie 90(10):1515-1522(2008)
- Wang, L., et al. Cell Motil. Cytoskeleton 65(7):581-593(2008)
- Hayashi, R., et al. J. Biol. Chem. 281(47):35633-35648(2006)
- Walker, M.G. Curr Cancer Drug Targets 1(1):73-83(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CDCA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-190 amino acids from the C-terminal region of human CDCA4.
NCBI Gene ID #:
55038
NCBI Official Name:
Cell division cycle-associated protein 4
NCBI Official Symbol:
CDCA4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa
Protein Accession #:
Q9BXL8
Protein GI Number:
32699606
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
Q9BXL8
User NOte:
Optimal dilutions for each application to be determined by the researcher.