NCK1 Antibody
| Code | Size | Price |
|---|
| PSI-57-226-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cytoplasmic protein NCK1, NCK adaptor protein 1, Nck-1, SH2/SH3 adaptor protein NCK-alpha, NCK1, NCK
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene is one of the signaling
and transforming proteins containing Src homology 2 and 3 (SH2 and
SH3) domains. It is located in the cytoplasm and is an adaptor
protein involved in transducing signals from receptor tyrosine
kinases to downstream signal recipients such as RAS. Alternatively
spliced transcript variants encoding different isoforms have been
found.
Background References:
- Barda-Saad, M., et al. EMBO J. 29(14):2315-2328(2010)
- Gehmlich, K., et al. Eur. J. Cell Biol. 89(5):351-364(2010)
- Preisinger, C., et al. Cell. Signal. 22(5):848-856(2010)
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NCK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-92 amino acids from the N-terminal region of human NCK1.
NCBI Gene ID #:
4690
NCBI Official Name:
Cytoplasmic protein NCK1
NCBI Official Symbol:
NCK1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
P16333
Protein GI Number:
127962
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
P16333
User NOte:
Optimal dilutions for each application to be determined by the researcher.