FGF7 Antibody
Code | Size | Price |
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PSI-55-081-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Fibroblast growth factor 7, FGF-7, Heparin-binding growth factor 7, HBGF-7, Keratinocyte growth factor, FGF7, KGF
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
The protein encoded by this gene is a member of the
fibroblast growth factor (FGF) family. FGF family members possess
broad mitogenic and cell survival activities, and are involved in a
variety of biological processes, including embryonic development,
cell growth, morphogenesis, tissue repair, tumor growth and
invasion. This protein is a potent epithelial cell-specific growth
factor, whose mitogenic activity is predominantly exhibited in
keratinocytes but not in fibroblasts and endothelial cells. Studies
of mouse and rat homologs of this gene implicated roles in
morphogenesis of epithelium, reepithelialization of wounds, hair
development and early lung organogenesis.
Background References:
- Lin, C.B., et al. J. Dermatol. Sci. 59(2):91-97(2010)
- Bando, M., et al. Immunol. Cell Biol. 88(3):328-333(2010)
- Wang, X., et al. Biomaterials 31(9):2542-2548(2010)
- Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This FGF7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-86 amino acids from the Central region of human FGF7.
NCBI Gene ID #:
2252
NCBI Official Name:
Fibroblast growth factor 7
NCBI Official Symbol:
FGF7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
P21781
Protein GI Number:
122756
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
P21781
User NOte:
Optimal dilutions for each application to be determined by the researcher.